With the use of Next Generation DNA/RNA Sequencing equipment (NGS) available at the Philippine Genome Center (PGC) in the University of the Philippines Diliman Campus, the team of the DNA Sequencing Core Facility (DSCF) is ready and willing to assist RITM and the DOH in confirming suspected cases of 2019-Novel Coronavirus (2019-nCoV) in the country.
Local dengue test kit to be marketed internationally
Manila HealthTek is a spinoff company formed to pursue the commercialization of the dengue diagnostic technology developed by a team of UP Manila National Institutes of Health medical researchers led by Dr. Raul Destura.
Non-Redundant and Overlapping Oncogenic Readouts of Non-Canonical and Novel Colorectal Cancer KRAS and NRAS Mutants
The efficacy of monoclonal antibodies targeting the epidermal growth factor receptor (EGFR) pathway for treatment of colorectal cancer (CRC) depends on predictive biomarkers that can identify likely responders or non-responders to therapy.
Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells
Renieramycin M (RM) is a KCN-stabilized tetrahydroisoquinoline purified from the blue sponge Xestospongia sp., with nanomolar IC50s against several cancer cell lines. Our goal is to evaluate its combination effects with doxorubicin (DOX) in estrogen receptor positive MCF-7 breast cancer cells.
PGC hosts One Health Bioinformatics and Grant Writing Workshop
This skill building workshop aims to freely integrate available molecular data from global repositories that are pertinent to locally circulating pathogens and apply it to research areas of interest for both the Biological Threat Reduction Program of the US government thru the Defense Threat Reduction Agency.
PGC researchers attend annual Human Genetics Meeting
Mr. Garrido and Ms. Alcantara shared the preliminary findings of the two Philippine Genome Center’s projects, “Mutational analysis of KRAS, NRAS, PIK3CA, BRAF, and PTEN genes in Filipino Colorectal Cancer Patients,” and “Detection and Functionalization of KRAS, NRAS, PIK3CA, BRAF, and PTEN Gene Mutations in Filipino Colorectal Cancer Patients,” through poster presentations.
Biotek-M Dengue Aqua Kit
The Biotek-M™ Dengue Aqua Kit is a diagnostic test designed to detect dengue infections in serum/plasma samples.
Read more about Dr. Raul Destura’s projects in NIMBB-UP Manila
NIMBB UP-NIH Projects Improving Molecular Diagnosis of Drug Resistant Tuberculosis (2016) Funding: US-NIH (RO1) Role: Principal Investigator Collaborators: University of California San Francisco Status: On-going Project 3D Targets: The UK-Philippine Research Consortium for Dengue Diagnostics and Drug Targets (2015) Funding: MRC-Newton Fund – PCHRD Role: Principal Investigator Collaborators: University of Glasgow and University of Bristol […]
Reynaldo L. Garcia, PhD
Dr. Garcia did postdoctoral work in New Zealand (University of Otago Medical School), Paris (Hopital de la Pitie-Salpetriere/Universite Pierre et Marie Curie), the United States (Case Western Reserve University School of Medicine) and London (University College London), before being appointed senior research scientist at Cancer Research UK’s Beatson Institute in Scotland. He has worked on Merck- and Roche-funded projects involving characterization of drug targets for pain and development of drug screening assays for disrupting cellular proliferation in cancer, respectively.
Catherine Lynn T. Silao, MD, PhD
She obtained her doctoral degree at the Kobe University Graduate School of Medicine, Kobe, Japan where she did work on the molecular basis of Glucose-6-Phosphate dehydrogenase deficiency (1) and of Maple Syrup Urine Disease (MSUD) among clinically diagnosed Filipino patients (2).