KRAS proto‑oncogene, GTPase (KRAS) functions as a molecular switch at the apex of multiple signaling pathways controlling cell proliferation, differentiation, migration, and survival. Canonical KRAS mutants, such as those in codons 12 and 13, produce constitutively active oncoproteins that short‑circuit epidermal growth factor receptor (EGFR)‑initiated signaling, resulting in dysregulated downstream effectors associated with cellular transformation.
A total of 34,958 high-confidence gene models were predicted and functionally associated to various economically important traits, such as pest/disease resistance, drought tolerance, coconut oil biosynthesis, and putative transcription factors.
While recent news of giant clams (Tridacna gigas) being harvested in the disputed Scarborough Shoal drew massive outrage online, it was only the latest low point in the dark history of wildlife exploitation in the region. A poignant series of cases also happened here in 2013 and 2014, this time involving pangolins or “scaly anteaters,” which have been described as the most trafficked animals in the world.
The internship program will be held on June 17 to July 26, 2019 at the 2nd floor, Left Wing, Philippine Genome Center Building, A. Ma. Regidor St., University of the Philippines, Diliman, Quezon City. Interested individuals from public and private colleges, universities, and research institutions nationwide are invited to apply. A stipend will be provided to help cover travel and living expenses.
Pals visited the PGC yesterday, March 28th, to see its core facilities and to talk about setting up assays for clinical testing, interpreting genetic testing services, and variant interpretations. He also met with Dr. Cynthia Saloma, PGC executive director; Dr. Raul Destura, PGC health program director; and Dr. Alexander Young, PGC research professor, to discuss the center’s readiness for genetic testing services.
If there is anything that Dr. Eva Cutiongco-de la Paz seems not to enjoy, it’s getting undue credit. The winner of the 2018 Dangal ng Bayan Award was admittedly nervous when her mother, a former faculty member at the UP College of Education, suggested having their photo taken with the tarpaulin celebrating her feat.
The Strategic Planning with the PGC Agriculture team was facilitated by PGC’s newly appointed Deputy Executive Director, Dr. Raul Destura. The activity was initiated by the PGC main office in order to weave the 6-year sustainability plan of the entire PGC.
The Department of Science and Technology (DOST) is tapping cutting edge genomics technology to develop precision medicine in the country and allow government health authorities to identify usually expensive, foreign developed medicines that are not really effective in controlling or curing Filipino diseases.
The Shared Genomics Core Laboratory (SGCL) at the Philippine Genome Center (PGC), UP Diliman was inaugurated on February 20 and officially handed over by the Commission on Higher Education (CHED) to the University.
Dr. Fauziah Rabbani (L), The Noordin M. Thobani Professor and Associate Vice Provost of the Research & Graduate Studies of the Aga Khan University, Pakistan, visits and tours the Philippine Genome Center with Dr. Cynthia Saloma (R), PGC Executive Director.