PHILIPPINE GENOME CENTER PUBLICATIONS

Artificial Intelligence-Assisted Loop Mediated Isothermal Amplification (ai-LAMP) for Rapid and Reliable Detection of SARS-CoV-2
Mohammed A Rohaim, Emily Clayton, Irem Sahin, Julianne Vilela, Manar E Khalifa, Mohammed Q Al-Natour, Mahmoud Bayoumi, Aurore Poirier, Manoharanehru Branavan, Mukunthan Tharmakulasingam, Nouman S Chaudhry, Ravinder Sodi, Amy Brown, Peter Burkhart, Wendy Hacking, Judy Botham, Joe Boyce, Hayley Wilkinson, Craig Williams, Michelle Bates, Roberto La Ragione, Wamadeva Balachandran, Anil Fernando, Muhammad Munir
medRxiv, July 2020


DNA Barcoding and Diversity Analysis of 19 Economically Important Philippine Sea Cucumbers (Holothuroidea)
Ma. Neda Alcudia-Catalma1§, Maria Genaleen Q. Diaz2, Roberta N. Garcia1, Pablo P. Ocampo2, Antonio C. Laurena1, and Evelyn Mae Tecson-Mendoza1*
Philippine Journal of Science, June 2020


Early Differential Expression of Galactomannan Biosynthesis Genes in ‘Makapuno’ Coconut (Cocos nucifera L.) revealed by the De Novo Assembly and Analysis of Endosperm Transcriptome
Jickerson P. Lado, Beatriz Z. Arellano, Cecille Ann L. Osio, Bernabeth Jo T. Tendero, Celia B. Dela Viña, Mary Ann O. Torio, Rita P. Laude, Maria Genaleen Q. Diaz
The Philippine Agricultural Scientist, 2020


Transcriptome Analysis of ‘Philippine Lono Tall’ Coconut (Cocos nucifera L.) Endosperm Reveals Differential Expression of Genes Involved in Oil Biosynthesis
Cecille Ann L. Osio, Genevieve Mae B. Aquino, Wilson F. Aala Jr., Jickerson P. Lado, Bernabeth Jo T. Tendero, Cristeta A. Cueto, Maria Genaleen Q. Diaz, and Rita P. Laude
The Philippine Agricultural Scientist, 2020


Secondary Metabolism in the Gill Microbiota of Shipworms (Teredinidae) as Revealed by Comparison of Metagenomes and Nearly Complete Symbiont Genomes
Marvin A. Altamia, Zhenjian Lin, Amaro E. Trindade-Silva, Iris Diana Uy, J. Reuben Shipway, Diego Veras Wilke, Gisela P. Concepcion, Daniel L. Distel, Eric W. Schmidt, Margo G. Haygood
Jillian Petersen, Editor
American Society for Microbiology Volume 5, Issue 3 (2020)


MicroRNA and mRNA interactions coordinate the immune response in non-lethal heat stressed Litopenaeus vannamei against AHPND-causing Vibrio parahaemolyticus
Pakpoom Boonchuen, Benedict A. Maralit, Phattarunda Jaree, Anchalee Tassanakajon & Kunlaya Somboonwiwat
Scientific Reports volume 10, Article number: 787 (2020)


Non-Redundant and Overlapping Oncogenic Readouts of Non-Canonical and Novel Colorectal Cancer KRAS and NRAS Mutants
Krizelle Mae M. Alcantara, Joshua Reginald P. Malapit, Ryan Timothy D. Yu, Jose Antonio Ma. G. Garrido, John Paul T. Rigor, Arlou Kristina J. Angeles, Eva Maria Cutiongco-de la Paz, and Reynaldo L. Garcia
Cells 2019 8(12)


Draft Genome Sequence of Multidrug-Resistant Vibrio parahaemolyticus Strain PH698, Infecting Penaeid Shrimp in the Philippines
Cynthia P. Saloma, Sarah Mae U. Penir, Joseph Matthew R. Azanza, Leobert D. dela Peña, Roselyn C. Usero, Nikko Alvin R. Cabillon, Angela Denise P. Bilbao and Edgar C. Amar
Microbiology 2019 Nov; 8(47): e01040-19


Draft Genome Sequence of Vibrio parahaemolyticus Strain PH1339, Which Causes Acute Hepatopancreatic Necrosis Disease in Shrimp in the Philippines
Sarah Mae U. Penir, Leobert D. dela Pena, Nikko Alvin R. Cabillon, Angela Denise P. Bilbao, Edgar C. Amar, Cynthia P. Saloma
Microbiology 2019 Nov 2019, 8 (46) e01020-19


Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells
Jortan O. Tun, Lilibeth A. Salvador-Reyes, Michael C. Velarde, Naoki Saito, Khanit Suwanborirux, and Gisela P. Concepcion
Marine Drugs 2019, 17(9), 536


Characterization of the Biosynthetic Potential of the β-proteobacterium Achromobacter xylosoxidans Strain ISP2-142-O-2-A Using Microbiological, Chemical, and Genomic Approaches
Miguel Azcuna, Lilibeth Salvador-Reyes, Jortan Tun, Arturo Lluisma1, Iris Diana Uy, Lovette Cunanan, Maria Auxilia Siringan, and Gisela P. Concepcion
Philippine Journal of Science


Phenotypic characterization of the novel, non‑hotspot oncogenic KRAS mutants E31D and E63K
Arlou Kristina J. Angeles, Ryan Timothy D. Yu, Eva Maria Cutiongco‑De la Paz, and Reynaldo L. Garcia
Oncology Letters 2019, 18(1)


De Novo Genome Sequence Assembly of Dwarf Coconut (Cocos nucifera L. ‘Catigan Green Dwarf’) Provides Insights into Genomic Variation Between Coconut Types and Related Palm Species
Darlon V. Lantican, Susan R. Strickler, Alma O. Canama, Roanne R. Gardoce, Lukas A. Mueller and Hayde F. Galvez
G3: GENES, GENOMES, GENETICS 2019, 9(8), 2377-2393


Effect of maternal supplement beverage with and without probiotics during pregnancy and lactation on maternal and infant health: a randomized controlled trial in the Philippines
Mantaring J, Benyacoub J, Destura R, Pecquet S, Vidal K, Volger S, Guinto V
BMC Pregnancy Childbirth 2018, 18(1): 193


Whole-genome sequencing and single nucleotide polymorphisms in multidrug-resistant clinical isolates of Mycobacterium tuberculosis from the Philippines
Roa MB, Tablizo FA, Morado EKD, Cunanan LF, Uy IDC, Ng KCS, Manalastas-Cantos KG, Reyes JM, Ganchua SKC, Ang CF, Kato-Maeda M, Cattamanchi A, Karaoz U, Destura RV, Lluisma AO
J Glob Antimicrob Resist 2018, 15: 239-245


Genotypic persistence of dengue virus in the Philippines
Galarion MJ, Schwem B, Pangilinan C, Dela Tonga A, Petronio-Santos JA, Delos Reyes E, Destura R.
Infect Genet Evol 2019, 69: 134-141


Non-additive effects of ACVR2A in preeclampsia in a Philippine population
Melissa D. Amosco†, Gloria R. Tavera†, Van Anthony M. Villar, Justin Michael A. Naniong, Lara Marie G. David-Bustamante, Scott M. Williams, Pedro A. Jose, and Cynthia P. Palmes-Saloma
BMC Pregnancy and Childbirth 2019, 19(11)


Whole genome sequencing and single nucleotide polymorphisms in multi-drug resistant clinical isolates of Mycobacterium tuberculosis from the Philippines
Roa MB, Tablizo FA, Morado EKD, Cunanan LF, Uy IDC, Ng KCS, Manalastas-Cantos KG, Reyes JM, Ganchua SKC, Ang CF, Kato-Maeda M, Cattamanchi A, Karaoz U, Destura RV, Lluisma AO
ScienceDirect 2018, 239-245


Discovery of chemoautotrophic symbiosis in the giant shipworm Kuphus polythalamia (Bivalvia: Teredinidae) extends wooden-steps theory
Distel DL; Altamia MA; Lin Z; Shipway JR; Han A; Forteza I; Antemano R; Limbaco MGJP; Tebo AG; Dechavez R; Albano J; Rosenberg G; Concepcion GP; Schmidt EW; Haygood MG
PNAS 2018, 239-245


Targeted next generation sequencing of the entire vitamin D receptor gene reveals polymorphisms correlated with vitamin D deficiency among older Filipino women with and without fragility fracture
M.P. Zumaraga, P. J. Medina, J. M. Recto, L. Abrahan, E. Azurin, C. Tanchoco, C. Jimeno, C. P. Saloma
ScienceDirect 2017, 98-108


Comparison of Two Massively Parallel Sequencing Platforms using 83 Single Nucleotide Polymorphisms for Human Identification
Apaga DL, Dennis SE, Salvador JM, Calacal GC, De Ungria MC
Scientific Reports 7, 398 (2017)


Establishment and Comparison of Two Different Diagnostic Platforms for Detection of DENV1 NS1 Protein
Tang Y, Chiu C, Lin C, Huang C, Chen Y, Destura R, Chao D and Wu C
Int J Mol Sci 2015; 16(11): 27850–27864


Middle ear microbiome differences in indigenous Filipinos with chronic otitis media due to a duplication in the A2ML1 gene
Santos-Cortez RP, Hutchinson DS, Ajami N, Reyes-Quintos MT, Tantoco MC, Labra P, Lagrana S, Pedro M, Llanes E, Gloria-Cruz T, Chan A, Cutiongco-de la Paz E, Belmont J, Chonmaitree T, Abes G, Petrosino J, Leal S and Chiong C
Infect Dis Poverty 2016; 5: 97


MicroRNA inhibition fine-tunes and provides robustness to the restriction point switch of the cell cycle
R.C.H. del Rosario, J.R.C.G. Damasco, B.D. Aguda
Scientific Reports 6: 32823 (2016)


Genetic and Environmental Determinants of Otitis Media in an Indigenous Filipino Population
Santos-Cortez RL, Reyes-Quintos MR, Tantoco ML, Abbe I, Llanes EG, Ajami NJ, Hutchinson DS, Petrosino JF, Padilla CD, Villarta RL Jr, Gloria-Cruz TL, Chan AL, Cutiongco-de la Paz EM, Chiong CM, Leal SM, Abes GT
Otolaryngol Head Neck Surg 2016; 155(5): 856-862


A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3
Leslie EJ, Liu H, Carlson JC, Shaffer JR, Feingold E, Wehby G, Laurie CA, Jain D, Laurie CC, Doheny KF, McHenry T, Resick J, Sanchez C, Jacobs J, Emanuele B, Vieira AR, Neiswanger K, Standley J, Czeizel AE, Deleyiannis F, Christensen K, Munger RG, Lie RT, Wilcox A, Romitti PA, Field LL, Padilla CD, Cutiongco-de la Paz EM, Lidral AC, Valencia-Ramirez LC, Lopez-Palacio AM, Valencia DR, Arcos-Burgos M, Castilla EE, Mereb JC, Poletta FA, Orioli IM, Carvalho FM, Hecht JT, Blanton SH, Buxó CJ, Butali A, Mossey PA, Adeyemo WL, James O, Braimah RO, Aregbesola BS, Eshete MA, Deribew M, Koruyucu M, Seymen F, Ma L, de Salamanca JE, Weinberg SM, Moreno L, Cornell RA, Murray JC, Marazita ML
Am J Hum Genet 2016; 98(4): 744-754


Evidence of TAF1 dysfunction in peripheral models of X-linked dystonia-parkinsonism
Domingo A, Amar D, Grütz K, Lee LV, Rosales R, Brüggemann N, Jamora RD, Cutiongco-Dela Paz E, Rolfs A, Dressler D, Walter U, Krainc D, Lohmann K, Shamir R, Klein C, Westenberger A
Cellular and Molecular Life Sciences 3205–3215(2016)


Characterization of the complete mitochondrial genome of Conus tribblei Walls, 1977.
Barghi, N., Concepcion, G. P., Olivera, B. M., Lluisma, A. O.
Mitochondrial DNA A DNA Mapp Seq Anal 2016 Nov; 27(6): 4451–4452.


Structural features of conopeptide genes inferred from partial sequences of the Conus tribblei genome
Barghi, N., Concepcion, G. P., Olivera, B. M., Lluisma, A. O.
Molecular Genetics and Genomics 291, 411–422(2016)


Comparing different post-mortem human samples as DNA sources for downstream genotyping and identification
Calacal G.C., Apaga D.T., Salvador J.M, Jimenez J.D., et.al.
Forensic Science International: Genetics 2015, 212-220


Comparison of the Venom Peptides and Their Expression in Closely Related Conus Species: Insights into Adaptive Post-speciation Evolution of Conus Exogenomes
Barghi N, Concepcion G.P., Olivera B.M., Lluisma A.O.
Genome Biology and Evolution 2015; 4;7(6):1797-814


Advancing Cryptosporidium Diagnostics from Bench to Bedside
Raul V. Destura, Rohani B. Cena, Ma. Jowina H. Galarion, Coleen M. Pangilinan, Geraldine M. Arevalo, Ryan Oliver C. Alba, Joy Ann G. Petronio, Gielenny M. Salem, Brian Schwem, Jesus Emmanuel A. D. Sevilleja
Current Tropical Medicine Reports 2, 150–160(2015)


High conopeptide diversity in Conus tribblei revealed through analysis of venom duct transcriptome using two high-throughput sequencing platforms
Barghi N, Concepcion G.P., Olivera B.M., Lluisma A.O.
Mar Biotechnology 2015; 17(1):81-98


A bioinformatics survey for conotoxin-like sequences in three turrid snail venom duct transcriptomes
David Thomas T. Gonzales, Cynthia P. Saloma
Toxicon (96):66-74


The mitochondrial genome of the red alga Kappaphycus striatus (“Green Sacol” variety): Complete nucleotide sequence, genome structure and organization, and comparative analysis
Francis A. Tablizo, Arturo O. Lluisma
Marine Genomics (18): 155-161


Continued circulation of a single genotype of dengue virus serotype 2 in the Philippines
Petronio JA, Vinarao RB, Flores KM, Destura RV
Asian Pacific Journal of Tropical Medicine 2014; 7(1): 30-33


Possible Loss of the Chloroplast Genome in the Parasitic Plant Rafflesia lagascae (Rafflesiaceae)
Jeanmaire Molina, Khaled M. Hazzouri, Daniel Nickrent, Matthe Geisler, Rachel S. Meyer, Melissa M. Pentony, Jonathan M. Flowers, Pieter Pelser, Julie Barcelona, Samuel Alan Inovejas, Iris Uy, Wei Yuan, Olivia Wilkins, Claire-Iphanise Michel, Selina LockLear, Gisela P. Concepcion, and Michael D. Purugganan
Mol Bio Evol 2014; 7(1): 30-33


Adaptive radiation of venomous marine snail lineages and the accelerated evolution of venom peptide genes
Olivera B.M., Watkins M., Bandyopadhyay P., Imperial J.S., de la Cotera E.P., Aguilar M.B., Vera E.L., Concepcion G.P., Lluisma A.O.
Ann N Y Acad Sci 2012; 1267: 61-70


Production of immunoglobulin Y (IgY) against synthetic peptide analogs of the immunogenic epitopes of the hepatitis B surface antigen
Guevarra Leonardo A; Leano Milagros B; Dalmacio Leslie M; Yu Gracia Fe B; Destura Raul V; Libranda-Ramirez Bernadette; Estacio Rhodora C
Acta medica Philippina 2012; 46(1): 14-21


Return to top