Artificial Intelligence-Assisted Loop Mediated Isothermal Amplification (ai-LAMP) for Rapid and Reliable Detection of SARS-CoV-2

Until vaccines and effective therapeutics become available, the practical way to transit safely out of the current lockdown may include the implementation of an effective testing, tracing and tracking system. However, this requires a reliable and clinically validated diagnostic platform for the sensitive and specific identification of SARS-CoV-2.

Early Differential Expression of Galactomannan Biosynthesis Genes in ‘Makapuno’ Coconut (Cocos nucifera L.) revealed by the De Novo Assembly and Analysis of Endosperm Transcriptome

Makapuno is a coconut cultivar with a naturally overproliferating solid endosperm almost filling the nut cavity. At 6-7 months after pollination (MAP), makapuno solid endosperm is phenotypically indistinguishable from the normal type Laguna Tall while at 8-9 MAP makapuno starts to soften and thicken in contrast to the hard and compact appearance of the normal. Here, the expression profiles of 6-7 and 8-9 MAP de novo assembled RNA Sequencing (RNA-Seq) transcriptomes of normal and makapuno were analyzed, and corresponding stages were compared to determine the differentially expressed genes (DEGs).

Transcriptome Analysis of ‘Philippine Lono Tall’ Coconut (Cocos nucifera L.) Endosperm Reveals Differential Expression of Genes Involved in Oil Biosynthesis

The ‘Philippine Lono Tall’ (PLNT) is a variant of the more common ‘Philippine Laguna Tall’ (LAGT), which produces fruits with soft endosperm and reported higher fat content. To understand patterns of fatty acid (FA) and oil accumulation in LAGT and PLNT fruits, transcriptomes of 6–7 month-old endosperm samples were analyzed by RNA-Seq. Quantitative PCR was performed to analyze the differential expression of selected genes related to oil biosynthesis. Further, oil samples from the PLNT endosperm were analyzed to determine their FA composition across developmental stages.

PGC Core Facility for Bioinformatics releases six (6) genome sequences of SARS-CoV-2 from Philippine samples between March 22-28, 2020

The Philippine Genome Center (PGC) thru its Core Facility for Bioinformatics (CFB) releases today to the global community through the GISAID database six (6) genomes of the SARS-CoV-2 sequences from Philippine samples taken in Metro Manila between 26 to 28 March 2020.

PGC’s Clinical Genomics Laboratory certified to conduct testing for COVID-19 (SARS-CoV-2) by Real-Time PCR

Upon completing and passing the Research Institute for Tropical Medicine’s (RITM) proficiency testing for SARS-CoV-2 detection by Real-Time PCR, the Clinical Genomics Laboratory (CGL) of the Philippine Genome Center is now certified to perform independent testing for COVID-19. The certification is released as of April 23, 2020 by the RITM-DOH.