PGC is a multidisciplinary institution that combines basic and applied research for the development of health and therapeutic products, and improved agriculture and aquatic resources. In the beginning it was attached to and subject to the control and supervision of the Office of the President (OP) of the University of the Philippines as approved by the UP Board of Regents during its 1246th meeting last July 31, 2009.

On February 26, 2016 the UP Board of Regents during its 1315th meeting approved the transfer of management and supervision from OP to the University’s Office of the Vice President for Academic Affairs (OVPAA).