Whole genome sequencing and single nucleotide polymorphisms in multi-drug resistant clinical isolates of Mycobacterium tuberculosis from the Philippines

Thousands of cases of multi-drug resistant Mycobacteria tuberculosis (MTB) have been observed in the Philippines but studies on the genotypes that underlie the observed drug resistance profiles have been lacking. This study aimed to analyse whole genomes of clinical isolates of MTB representing varying resistance profiles to identify single nucleotide polymorphisms (SNPs) in resistance-associated genes.

PGC researchers attend annual Human Genetics Meeting

Mr. Garrido and Ms. Alcantara shared the preliminary findings of the two Philippine Genome Center’s projects, “Mutational analysis of KRAS, NRAS, PIK3CA, BRAF, and PTEN genes in Filipino Colorectal Cancer Patients,” and “Detection and Functionalization of KRAS, NRAS, PIK3CA, BRAF, and PTEN Gene Mutations in Filipino Colorectal Cancer Patients,” through poster presentations.

2017 Year-end Review and R&D Planning

The Philippine Genome Center conducted its Year-end review and R&D planning last December 12, 2017 at the Banyan/Cedar Hall, Richmonde Hotel, Ortigas, Pasig City. Dr. Cynthia P. Saloma, PGC Executive Director opened the meeting by welcoming the attendees comprised of the PGC executive committee, R&D program directors, project leaders, core facility and administrative staff. Dr. Saloma emphasized the importance of planning the projected Key Performance Indicator of the center and streamlining its operations for the next five years.