CHED, UP & DOST unveil shared genomics core laboratory

Feb 20, 2019 – The Shared Genomics Core Laboratory (SGCL) is a research and service laboratory for high-throughput genomics research. It boasts highly-advanced equipment units that will now be available and accessible to researcher and students from universities and research institutions across the country. The SGCL was made possible through the support of the Commission … Continue reading CHED, UP & DOST unveil shared genomics core laboratory

Whole-genome sequencing and single nucleotide polymorphisms in multidrug-resistant clinical isolates of Mycobacterium tuberculosis from the Philippines

Thousands of cases of multidrug-resistant tuberculosis (TB) have been observed in the Philippines, but studies on the Mycobacterium tuberculosis (MTB) genotypes that underlie the observed drug resistance profiles are lacking. This study aimed to analyse the whole genomes of clinical MTB isolates representing various resistance profiles to identify single nucleotide polymorphisms (SNPs) in resistance-associated genes.

Non-additive effects of ACVR2A in preeclampsia in a Philippine population

Multiple interrelated pathways contribute to the pathogenesis of preeclampsia, and variants in susceptibility genes may play a role among Filipinos, an ethnically distinct group with high prevalence of the disease. The objective of this study was to examine the association between variants in maternal candidate genes and the development of preeclampsia in a Philippine population