As the first ever omics facility in Mindanao, PGC Mindanao aims to conduct advance and molecular genomic tests in Mindanao as its contribution to the government response in managing and controlling the Emerging and reemerging livestock diseases.
SARS-CoV-2 lineage P.3 first detected in the Philippines labeled as ‘Theta’ by WHO
The recommendation is to use letters of the Greek Alphabet, i.e., Alpha, Beta, Gamma to label the variants. As such, Variant of Interest (VOI) P.3 which was first detected in the Philippines (Jan-21)1 is now labeled by WHO as Theta.
Nutritional properties and phenolic acid profile of selected Philippine pigmented maize with high antioxidant activity
Ten (10) accessions of pigmented maize collected from the various regions in the Philippines with the highest antioxidant activity were evaluated for several chemical and nutritional parameters such as proximate composition, carbohydrate profile (starch, amylose and amylopectin contents), phenolic acid, mineral (iron and zinc) and food energy contents.
Genetic Structure and Diversity of Banana Bunchy Top Virus (BBTV) in the Philippines
Banana bunchy top virus (BBTV) is an important disease of banana in the Philippines and in other banana-producing countries. This study was conducted to investigate the genetic structure and diversity of Philippine BBTV isolates which remain unexplored in the country. BBTV-infected plant tissues were sampled from banana-growing provinces (i.e., Cagayan, Isabela, Quirino, Batangas, Laguna, Rizal, Quezon, Palawan, Cebu, Leyte, and Davao del Sur) and the partial DNA-R gene of BBTV was sequenced.
In Vitro Lipid-lowering Properties of the Fruits of Two Bignay [Antidesma bunius (L.) Spreng] Cultivars as Affected by Maturity Stage and Thermal Processing
Bignay [Antidesma bunius (L). Spreng] fruit contains an array of polyphenols and information on how these bioactive compounds vary with cultivar type, maturity stage, and process treatment are unclear. Also, the effects of these variations on the lipid-lowering potential of this Philippine indigenous berry have not been reported.
PGC SARS-CoV-2 Bulletin No. 7: Detection and characterization of a new SARS-CoV-2 lineage P.3, with spike protein mutations E484K, N501Y, P681H and LGV 141-143 deletion, from samples sequenced through the intensified UP-PGC, UP-NIH and DOH biosurveillance program
A close examination of the mutation profile of the P.3 viruses revealed that apart from E484K and N501Y, they also share other spike protein mutations that are likely to have functional significance (Figure 2). This includes the P681H mutation, also found in lineage B.1.1.7 viruses, as well as a three-amino acid deletion at positions 141 to 143 (LGV141_143del).
PGC SARS-CoV-2 Bulletin No. 6: First case of the new variant under Lineage B.1.1.7 detected in the Philippines
Through the biosurveillance efforts of the UP – Philippine Genome Center (PGC), in coordination with the Department of Health (DOH) – Epidemiology Bureau and the Inter-Agency Task Force (IATF) Task Force on COVID-19 Variants, we report the first confirmed case of the SARS-CoV-2 B.1.1.7 lineage, more commonly known as the UK variant, in the Philippines. An announcement of this finding can be found in an official DOH press release dated January 13, 2021.
PGC SARS-CoV-2 Bulletin No. 5: New Variants from UK and South Africa NOT detected in 305 local viral samples
Recently, new SARS-CoV-2 variants were detected in the United Kingdom and South Africa with multiple spike protein mutations that may cause substantial changes in certain properties of the virus. These observations spurred biosurveillance efforts in different countries, with some countries outside of the UK and South Africa already reporting the presence of these new variants within their territories. The data presented in this report is part of our own continuing biosurveillance efforts to track the entry of these new variants in the country, as well as other viral mutations that may be of concern locally.
OnePGC: Luzon, Visayas, and Mindanao Virtual Conference 12.10.2020 #PGCParaSaBayan
Philippine Genome Center’s virtual conference on December 10, 2020. More information about this event: https://bit.ly/Program_1PGC2020 OnePGC 2020 phgenome Communications Team