Phosphatase and tensin homolog deleted on chromosome 10, or PTEN, is a well-characterized tumor suppressor with both lipid and protein phosphatase activities. PTEN is often downregulated by epigenetic mechanisms such as hypermethylation, which leads to constitutive activation of the PI3K–Akt pathway.
GxB CON 2021: Overcoming Challenges, Building Opportunities
The Philippine Genome Center (PGC) is hosting the Genomics and Bioinformatics Conference 2021 on December 7-9, themed Overcoming Challenges, Building Opportunities—the 3-day conference will consist of talks from experts in health, agriculture, livestock, and fisheries as well as in biodiversity, ethnicity, and forensics.
High rates of tenofovir failure in a CRF01_AE-predominant HIV epidemic in the Philippines
The Philippines has the fastest growing HIV epidemic in the Asia-Pacific. This increase was accompanied by a shift in the predominant HIV subtype from B to CRF01_AE. Increasing evidence points to a difference in treatment responses between subtypes. We examined treatment failure and acquired drug resistance (ADR) in people living with HIV (PLHIVs) after one year on antiretrovirals (ARVs).
Non-Redundant and Overlapping Oncogenic Readouts of Non-Canonical and Novel Colorectal Cancer KRAS and NRAS Mutants
The efficacy of monoclonal antibodies targeting the epidermal growth factor receptor (EGFR) pathway for treatment of colorectal cancer (CRC) depends on predictive biomarkers that can identify likely responders or non-responders to therapy.
The gene doctor will see you now
If there is anything that Dr. Eva Cutiongco-de la Paz seems not to enjoy, it’s getting undue credit. The winner of the 2018 Dangal ng Bayan Award was admittedly nervous when her mother, a former faculty member at the UP College of Education, suggested having their photo taken with the tarpaulin celebrating her feat.
Informatics in Biomedical Research & Health
A workshop on “Informatics in Biomedical Research & Health”
Genomics: The Path Towards A Better Understanding of Health, Disease, Evolution And Biodiversity
The Philippine Genome Center will hold a scientific symposium entitled “Genomics: The Path Towards A Better Understanding of Health, Disease, Evolution And Biodiversity” at the National Institute of Physics Auditorium, National Science Complex, UP Diliman campus.