#PGCTalks – PPMF Webinar

Expanding the Field of Omics Research in the Philippines: A Glimpse into the World of Proteins, Proteomics, and Metabolomics #PGCTalks REGISTER Date: November 15, 2021, Friday, 1:15-3:10pm This webinar is open to the public and registration is free. Registration will close on November 10, 2021. Newly launched PGC core facility PPMF is hosting #PGCTalks on […]

High Performance Computing and Data Science Workflow in Julia

HPC and Data Science Workflow in Julia #PGCTalks Date: July 16, 2021, Friday, 4:30-6:00pm This webinar is open to the public and registration is free. Abstract Julia is specifically designed from the start of its conception as a language for high-performance computation but at the same time highly interactive. To achieve this, Julia is one […]

cheryl_andam

A tale of sex: gene sharing between microbial species, genomes and microbiomes

Horizontal gene transfer (HGT) is an important evolutionary process that allows the spread of innovations between distantly related organisms. In this webinar, I will present recent findings on the process, driving factors and impacts of HGT in light of recent developments in next-generation sequencing approaches. I will discuss examples of HGT within species, between species and between microbial communities, and how these gene exchange networks drive the genetic and phenotypic diversity of microbes in nature and clinical settings

ido_goldstein

Transcription Factor Assisted Loading and Enhancer Dynamics Dictate the Hepatic Fasting Response

Fasting elicits transcriptional programs in hepatocytes leading to glucose and ketone production. This transcriptional program is regulated by many transcription factors (TFs). To understands how this complex network regulates the metabolic response to fasting we aimed at isolating the enhancers and TFs dictating it. Measuring chromatin accessibility revealed that fasting massively reorganizes liver chromatin, exposing numerous fasting-induced enhancers.

kumar_selvarajoo

Systems Biology to Overcome TRAIL Resistance in Cancer Treatment

Over the last decade, our research team has investigated the dynamic responses and global properties of living cells using systems biology approaches. More specifically, we have developed computational models and statistical techniques to interpret instructive cell signaling and high-throughput transcriptome-wide behaviors of immune, cancer, and embryonic development cells.

michael_hucka

SBML (the Systems Biology Markup Language) and related resources for computational systems biology

Computational modeling allows biologists to create formal models of cellular phenomena that can be simulated, analyzed and compared to experimental data. Biologists today have at their disposal a wide range of software tools for their modeling efforts. The wealth of resources is a boon to researchers, but it also presents interoperability problems.