Previously within an indigenous Filipino community with a ~50% prevalence of otitis media, we identified an A2ML1 mutation that confers a high risk of otitis media susceptibility and influences the relative abundance of specific bacterial taxa within the middle ear.
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Genetic and Environmental Determinants of Otitis Media in an Indigenous Filipino Population
To identify genetic and environmental risk factors for otitis media in an indigenous Filipino population. Cross-sectional study.Indigenous Filipino community.Clinical history and information on breastfeeding, tobacco smoke exposure, and swimming were obtained from community members.