Previously within an indigenous Filipino community with a ~50% prevalence of otitis media, we identified an A2ML1 mutation that confers a high risk of otitis media susceptibility and influences the relative abundance of specific bacterial taxa within the middle ear.
Genetic and Environmental Determinants of Otitis Media in an Indigenous Filipino Population
To identify genetic and environmental risk factors for otitis media in an indigenous Filipino population. Cross-sectional study.Indigenous Filipino community.Clinical history and information on breastfeeding, tobacco smoke exposure, and swimming were obtained from community members.