Previously rare A2ML1 variants were identified to confer otitis media susceptibility in an indigenous Filipino community and in otitis-prone US children.
Genetic and Environmental Determinants of Otitis Media in an Indigenous Filipino Population
To identify genetic and environmental risk factors for otitis media in an indigenous Filipino population. Cross-sectional study.Indigenous Filipino community.Clinical history and information on breastfeeding, tobacco smoke exposure, and swimming were obtained from community members.