A webinar hosted by the Program on Biodiversity, Ethnicity, and Forensics of the Philippine Genome Center and the Institute of Biology, University of the Philippines Diliman Focusing on Philippine Biodiversity: The Philippine BioGenome Project The Philippine BioGenome Project (PBGP) is a research initiative headed by the PGC Program on Biodiversity, Ethnicity, and Forensics (PBEF). The […]
Call for Applications: PGC Bioinformatics Training & Internship Program 2022
The PGC-Core Facility for Bioinformatics is inviting Filipino college students and young professionals in science and engineering for an online training and internship program in bioinformatics.
Methods used in microbial forensics and epidemiological investigations for stronger health systems
Establishing and maintaining a national microbial forensic system to strengthen capacities in conducting forensic and epidemiological investigations should be prioritised by all countries, accompanied by a national policy that sets the legislative framework and provides for the system’s financial requirements.
Call for Applications: Metagenomics Bioinformatics Workshop
The PGC Core Facility for Bioinformatics, together with Noveaulab and PacBio, are conducting a two-day online training workshop on the bioinformatics analysis of 16S metagenomic data using PacBio reads. This event will be held on April 18-19, 2022 (Mon-Tue) at 1:00-5:00 PM. Interested individuals from public and private colleges, universities, and research institutions in the […]
Challenges on the Development of Biodiversity Biobanks: The Living Archives of Biodiversity
In this review, we highlight the necessity for biodiversity biorepositories by presenting their significant role in health, biodiversity, linking of big data, other translational research, and biodiversity conservation efforts.
Single nucleotide polymorphism (SNP) in genes of lupus: A Philippine study (SIGLA-PH)
Eight SNPs were found to be associated with the development of SLE among Filipinos. Similar to previous genetic studies in lupus patients, majority of the SNPs were found in the major histocompatibilty complex genes in the HLA region. Our study identified two unique SNPs that will be validated as potential diagnostic markers for SLE. The findings of this study may contribute to the development of a polygenic risk score in determining susceptibility to SLE among Filipinos.
PPMF hosts #PGCTalks webinar on Feb. 28, 2022
#PGCTalks – PPMF webinar Protein Analysis, Instrumentation, and Applications Webinar The Protein, Proteomics, and Metabolomics Facility is hosting a #PGCTalks webinar on February 28, 2022 at 1 – 4 pm. Invited speakers will discuss the basic principles and applications of FPLC, Multiwavelength Spectrophotometer, and Circular Dichroism Spectropolarimeter. A Question-and-Answer portion will be held after the presentations. […]
PGC SARS-CoV-2 Bulletin No. 8: Detection of the first 500 SARS-CoV-2 Omicron Variant in the Philippines
This variant, with its more than 30 mutations in the Spike region is hypothesized to be over twice as infectious and twice more likely to escape current vaccines than the Delta variant. Currently, Omicron consists of four (4) phylogenetic lineages: the main lineage B.1.1.529 and its three (3) sublineages: BA.1, BA.2, and BA.3. Based on global statistics, BA.1 is the predominant Omicron lineage being detected worldwide, but a recent increase in the proportion of BA.2 cases has also been observed.
The Novel Phosphatase Domain Mutations Q171R and Y65S Switch PTEN from Tumor Suppressor to Oncogene
Phosphatase and tensin homolog deleted on chromosome 10, or PTEN, is a well-characterized tumor suppressor with both lipid and protein phosphatase activities. PTEN is often downregulated by epigenetic mechanisms such as hypermethylation, which leads to constitutive activation of the PI3K–Akt pathway.