SPR Analysis

This is a biosensor technique that is used in studying binding kinetics and affinity of molecular interactions. Choice between single- or multi-cycle kinetics is possible with the BiacoreTM X100 System.

Utilize a chip that is compatible with a broad range of applications such as basic research, quality control, ligand fishing, and fragment-based drug discovery (FBDD). Ligands are covalently coupled via functional groups such as -NH2, -SH, -CHO, -OH, and -COOH.

Perform SPR using a chip designed to bind different types of histidine-tagged molecules such as recombinant proteins via metal chelation. This chip could be used from low-molecular weight analytes to large proteins.