The Centre for Biodiversity Genomics (CBG) is a research organization dedicated to furthering our understanding of the world’s fauna and flora. Through a variety of approaches, researchers at the institute are discovering, cataloging, and describing biodiversity. DNA barcoding, an innovative technique developed at CBG, utilizes DNA sequencing technology for species identification.
Economic Opportunities in Genomics
Over 20 of the Philippines’ biggest names in biotechnology and investment gathered last November 12, 2016 at a symposium hosted by the Philippine Genome Center (PGC) at the National Institute of Molecular Biology and Biotechnology with the aim of sharing insights on the scientific and economic value of genomics.
A tale of sex: gene sharing between microbial species, genomes and microbiomes
Horizontal gene transfer (HGT) is an important evolutionary process that allows the spread of innovations between distantly related organisms. In this webinar, I will present recent findings on the process, driving factors and impacts of HGT in light of recent developments in next-generation sequencing approaches. I will discuss examples of HGT within species, between species and between microbial communities, and how these gene exchange networks drive the genetic and phenotypic diversity of microbes in nature and clinical settings
Transcription Factor Assisted Loading and Enhancer Dynamics Dictate the Hepatic Fasting Response
Fasting elicits transcriptional programs in hepatocytes leading to glucose and ketone production. This transcriptional program is regulated by many transcription factors (TFs). To understands how this complex network regulates the metabolic response to fasting we aimed at isolating the enhancers and TFs dictating it. Measuring chromatin accessibility revealed that fasting massively reorganizes liver chromatin, exposing numerous fasting-induced enhancers.
Systems Biology to Overcome TRAIL Resistance in Cancer Treatment
Over the last decade, our research team has investigated the dynamic responses and global properties of living cells using systems biology approaches. More specifically, we have developed computational models and statistical techniques to interpret instructive cell signaling and high-throughput transcriptome-wide behaviors of immune, cancer, and embryonic development cells.
Cracking the biological code: insights from Dr. Dawn Field
We’re used to thinking of codes as long strings of seemingly indecipherable characters – languages known to computer programmers. However, there exists another, more significant code found within us and around us: DNA, our planet’s biological code.
International Conference on Biodiversity & Chemical Biology
International Conference on Biodiversity & Chemical Biology
A Convergent, Multidisciplinary Approach Towards Developing Microphysiological Systems: Tissues-on-Chips for Pharmacological Safety and Efficacy Testing
Advances in basic and preclinical science continue to fuel the drug discovery pipeline, however only a small fraction of compounds meet criteria for approval by the FDA.
SBML (the Systems Biology Markup Language) and related resources for computational systems biology
Computational modeling allows biologists to create formal models of cellular phenomena that can be simulated, analyzed and compared to experimental data. Biologists today have at their disposal a wide range of software tools for their modeling efforts. The wealth of resources is a boon to researchers, but it also presents interoperability problems.
TGIF Seminar: September 30, 2016
Held usually at 3:30pm on Fridays, TGIF discussions are informal talks on current scientific topics and events. The gathering is sponsored by the PGC, NIMBB (National Institute of Molecular Biology & Biotechnology) at UP Diliman, and the IB (Institute of Biology) at UP Diliman.