MicroRNA inhibition fine-tunes and provides robustness to the restriction point switch of the cell cycle

The restriction point marks a switch in G1 from growth factor-dependent to growth factor-independent progression of the cell cycle. The proper regulation of this switch is important for normal cell processes; aberrations could result in a number of diseases such as cancer, neurodegenerative disorders, stroke and myocardial infarction.

Adaptive radiation of venomous marine snail lineages and the accelerated evolution of venom peptide genes

Olivera B.M., Watkins M., Bandyopadhyay P., Imperial J.S., de la Cotera E.P., Aguilar M.B., Vera E.L., Concepcion G.P., Lluisma A.O.

An impressive biodiversity (>10,000 species) of marine snails (suborder Toxoglossa or superfamily Conoidea) have complex venoms, each containing approximately 100 biologically active, disulfide-rich peptides. In the genus Conus, the most intensively investigated toxoglossan lineage (∼500 species), a small set of venom gene superfamilies undergo rapid sequence hyperdiversification within their mature toxin regions.