Whole genome sequencing and single nucleotide polymorphisms in multi-drug resistant clinical isolates of Mycobacterium tuberculosis from the Philippines

Thousands of cases of multi-drug resistant Mycobacteria tuberculosis (MTB) have been observed in the Philippines but studies on the genotypes that underlie the observed drug resistance profiles have been lacking. This study aimed to analyse whole genomes of clinical isolates of MTB representing varying resistance profiles to identify single nucleotide polymorphisms (SNPs) in resistance-associated genes.

Training of Experts from Cambodia, Brunei, Lao PDR, Myanmar, and Philippines on Genomics and Bioinformatics

The Philippine Genome Center supported by the Philippine Council for Agriculture, Aquatic and Natural Resources Research and Development (PCAARRD) – Department of Science and Technology (DOST) organized a workshop for representatives from some of the participating ASEAN countries during the 9th Informal ASEAN Ministerial Meeting on Science and Technology (IAMMST-9) held in October 2016. Project … Continue reading Training of Experts from Cambodia, Brunei, Lao PDR, Myanmar, and Philippines on Genomics and Bioinformatics

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Bioinformatics in Influenza surveillance: From sequence to structure to molecular mechanisms with the FluSurver

Date: Tuesday, 21 June 2016, 10 am (Manila Time)
Abstract – Bioinformatics can play an important role in infectious disease surveillance and research from epidemiological data processing with geographic and temporal visualization to comparing genome phylogenies and structural modelling of mutations. As a classical example, interest in new influenza outbreaks as well as regular surveillance of circulating seasonal strains produce a constant flow of influenza genome sequences that need to be analysed and interpreted for epidemiological and phenotypic features.