In line with the vision and mission of the Philippine Genome Center, the Health Program will utilize genomics research to develop diagnostic kits for early diagnosis and treatment of communicable and non-communicable diseases; expand strategic biogenomic surveillance and forecasting system in the Philippines; identify drug resistant strains and new strains during epidemics and outbreaks; and advance pharmacogenomics.
The applications of genomics in medicine involve diagnosis, prognosis, prevention and/or treatment of diseases. Genomics is expected to transform health care delivery through personalized medicine. This wide array of potential applications of genomics in health involve:
- the identification of genetic variations among individuals that can act as biomarkers for increased susceptibility to infectious diseases such as dengue, tuberculosis and malaria as well as non-communicable diseases such as heart disease, diabetes and cancer;
- discovery of novel therapeutic targets through a better understanding of molecular mechanisms and disease pathways; and
- development of personalized medicine for optimum, individualized treatment for every Filipino.
- Clinical Validation Study of the BIOTEK-M Dengue Kit (BACT)/“LAB-IN-A-MUG” Project
- Regional Roll-Out Of BIOTEKL-M DENGUE-AQUA KIT (Liquid Format) (R2OB)
- Product Development of BIOTEK-M DENGUE-SECO (Lyophilized Format) (SECO)
- A Web-based Interactive Genome Library for Surveillance, Detection, Characterization and Drug-Resistance Monitoring of Influenza Virus Infection in the Philippines
- Genomic Association Studies in Filipinos on Treatment, Diagnosis and Risk Assessment of Type 2 Diabetes Mellitus and Its Related Medical Condition
- Evaluation of Candidate Genetic Variations as Pharmacogenetic Markers for Commonly used Oral Hypoglycemic Agents among Filipinos
- Correlation of Candidate Genetic Variations for Susceptibility and Risk Assessment of Type 2 Diabetes Mellitus and its Related Medical Conditions
- Transcriptional Profiling and Pathway Analyses for Complications of Type 2 Diabetes Mellitus
- Genomic Research on Hypertension, Coronary Artery Disease and Dyslipidemia towards the Development of Individualized Diagnostic and Therapeutic Strategies
- Pharmacogenetic Studies on some commonly used Drugs for Hypertension, Dyslipidemia and Coronary Artery Disease among Filipinos
- Prevalence of Genetic Polymorphism Associated with the Risk for the Development of Hypertension, Dyslipidemia and Coronary Artery Disease among Filipinos
- Detection and Functional Characterization of KRAS, PIK3CA, BRAF, PTEN and AKT1 Gene Mutations in Filipino Colorectal Cancer Patients
- Mutational Analysis of KRAS, PIK3CA, BRAF, PTEN and AKT1 Gene Mutations in Filipino Colorectal Cancer Patients
- Functional Characterization of Novel Mutations in Downstream Effectors of the EFGR Signaling Pathway among Filipino Colorectal Cancer Patients
- Development of Mutation Detection Assay for Identifying likely Responders to EFGR-targeted Therapy
Email [email protected] should you wish to collaborate.